http://localhost:80/xmlui/handle/123456789/12856 2026-04-12T00:29:02Z http://localhost:80/xmlui/handle/123456789/13161 Title: Early Experience of Laparoscopy in Emergency Operation Theatre at Lahore General Hospital, Lahore Authors: AKHTAR, AHMAD NAEEM; AHMAD, MUHAMMAD SHABBIR; KHOKHAR, MUHAMMAD IMRAN; AFZAL, MUHAMMAD FAROOQ Abstract: Laparoscopic surgical intervention has revolutionised the exposure of General surgeons in both diagnostic as well as therapeutic procedures in surgical emergency department at Lahore General Hospital, Lahore. It has helped the surgeons to make the Diagnosis with Laparoscope and then proceed in cases of blunt abdominal trauma, mesenteric bowel ischemia, ruptured ectopic pregnancy, sealed adhesion obstruction and duodenal ulcer perforation. At the same time Laparoscope in emergency has helped the patients of acute appendicitis and abdomen TB patients by their post operative pain, hospital stay, scar mark and early return to normal routine after surgery. It has really proved excellent in all the patients who underwent surgery with its help but still more data is needed to prove its value. 2017-12-01T00:00:00Z http://localhost:80/xmlui/handle/123456789/13158 Title: Her-2/ c-erb B 2 receptors Expression in Benign Fibroepithelial Lesions – Fibroadenomas; with Realtion to age of patients Authors: BUTT, SABAHAT JAVAID; ALAM, MUJAHID; MUHAMMAD, ASHRAF Abstract: Background: Fibroadenomas are benign breast tumours that are commonly diagnosed in young woman and are associated with slight increase in the risk of breast cancer. The lesions vary considerably in their histologic characteristics. Her-2/neu (c-erb-B2) oncogene is a member of epidermal growth factor receptor family and its amplification is one of the most common genetic alterations associated with human breast tumours. Aim: To evaluate any correlation between HER-2 /neu/c-erb B2 immunostaining expression in benign fibroepithelial lesions - fibroadenoma and its correlation with specific age group. Methodology: This study was based on the principle that Her-2 / neu antigen is demonstrated using Avidin –Biotin peroxidase complex method of immunostaining in 25 cases of fibroadenoma. Results: The results showed that 56% cases took no immunostaining, 28% cases showed faint (+) level of immunostaining while 16% cases exhibited moderate (++) level of expression. No benign fibroepithelial lesion manifested intense (+++) level of staining. Conclusion: The age range in 25 patients of fibroadenoma was 15-38 years with mean age 24.4 +/- 6.59 years. In fibroadenoma group, out of 25 cases, 4 cases (16%) showed a moderate (2+) level of Her-2 over-expression. 2017-12-01T00:00:00Z