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Short communication: studies on punica granatum-I isolation and identification of some constituents from the seeds of punica granatum

Sun, 08 Jan 1995 00:00:00 GMT

Title: Short communication: studies on punica granatum-I isolation and identification of some constituents from the seeds of punica granatum Authors: R Ahmed; S M Ifzal; A Saifuddin; M Nazeer Abstract: Initial phytochemical screening of the seeds of Punica granatum has revealed the presence of Ursolic acid and beta-Sitosterol alongwith a long straightchain hydrocarbon - nonacosene. Presence of estrogens and glycosides have also been detected.

Short communication: guidelines to good manufacturing practices (g.m.p.) in pharmaceutical manufacturing

Sat, 07 Jan 1995 00:00:00 GMT

Title: Short communication: guidelines to good manufacturing practices (g.m.p.) in pharmaceutical manufacturing Authors: R H Shaikh; A A Sial Abstract: The object of the GMP and associated rules is the assurance of the quality of the products for the safety, well being and protection of the patient. In achieving this aim it is impossible to over-emphasise the importance of people, at all levels, in the assurance of the quality of medicinal products. The great majority of reported defective medicinal products has resulted from human error or carelessness and not from failure in technology. All the people involved with the production, quality control or distribution of medicinal products, whether key personnel, production or quality control staff, inspectors or other involved in the many activities which lead to a patient taking a medicine, should bear this constantly in mind when performing their duties.

Studies on the antimicrobial activity of honey

Thu, 06 Jan 1994 00:00:00 GMT

Title: Studies on the antimicrobial activity of honey Authors: D Sheikh; S Zaman; S B Naqvi; M R Sheikh; G Ali Abstract: Ten samples of crude and processed honey were used to determine antimicrobial activity against twenty five species of pathogenic and nonpathogenic bacteria, commonly encountered in human infections. The antifungal activity was checked against ten parasitic and saprophytic fungi. Most of the samples of honey used in the study showed broad spectrum antibacterial and promising antifungal activity

Effect of cimetidine, ranitidine and tiotidine on plasma testosterone and luteinizing hormone levels in rats

Thu, 06 Jan 1994 00:00:00 GMT

Title: Effect of cimetidine, ranitidine and tiotidine on plasma testosterone and luteinizing hormone levels in rats Authors: R T Mahmud; M S Akhter Abstract: This investigation was carried out to study the comparative effects of cimetidine, ranitidine and tiotidine on the plasma levels of testosterone and luetinizing hormone under local conditions. The three H(2)-blocking drugs were injected to the adult male albino rats twice daily at the recommended therapeutic dose levels for six weeks. The data obtained showed that only tiotidine caused a significant (<0.05) increase in the level of testosterone. However, all the three drugs caused a significant rise in the levels of luteinizing hormone with the most active ranitidine administration.