Isolation and Structural Studies on the Chemical Constituents of some Indigenous Flowering Plants

Abstract

In the present project work was carried out on the isolation and structure of the chemical constituents of the following plants of Pakistan. • Nepeta Hindustana • Prosopis Juliflora • Euphorbia Granulata The work on Nepeta hindustana led to the isolation of four new triterpenes named as nepeticin, nepetilin, nepetidin and neheptin, besides hentriaconatane, wax sitosterol, oleanolic acid, sitosterol glucoside and the flavonoids, dination, 7,4-dimethylscutellarine and nepetine. The structural of two newtritepenes nepeticin and nepeticin and nepetidin were eluciadated completely. From the mesquite plant Prosopis juliflora, a number of alkaloida were isolated. The absolute configuration of juliflorine, an alkaloid reported earlier by the present authors was determined by spectroscopic means. The main alkaloid of this plant namely juliflorine was found to inhibit the growth of a number of pathogenic bacteria and fungi. From the neutral portion triacontanol sit sterol and its glycoside were isolated. The preliminary work on Euphorbia granulata led to the isolation of several neutral compounds (hydrocarbons esters and triterpenes) which are under investigation.