Clinical efficacy and CT perfusion of puerarin combined with naloxone in the treatment of traumatic cerebral infarction

Abstract

Puerarin is an important active ingredient of Radix puerariae. Puerarin is an isoflavone compound Z clinical and basic research proves that S. puerarin can increase cerebral circulation blood flow; increase cerebral perfusion; reduce blood viscosity and improve microcirculation. The present research was conducted to observe the clinical efficacy of puerarin combined with naloxone in the treatment of traumatic cerebral infarction (TCI). Methods 52 patients with TCI were randomly divided into two groups. The treatment group was treated with puerarin and naloxone and the control group was treated with conventional therapy. Results: The total effective rate was 82% in the treatment group, which was better than 61% in the control group. The difference was statistically significant (p<0.05). The efficacy of simple TCI in both groups was significantly better than that of TCI with brain contusion; the effect of intracranial hemorrhage and the effect of TCI alone in the two groups; the treatment group was significantly better than the control group (p<0.05). Conclusion: The combination of puerarin and naloxone in the treatment of TCI can improve the curative effect.