Identification of the risk factors of the thyroid cancer by using logit model in Lahore

Abstract

Thyroid Cancer is a disease, which becomes a cause of death in developing countries. The aim of this study is to investigate all the possible risk factors of thyroid cancer in Pakistan. This study was consisting of 320 individuals,including 160 cases and 160 controls. These subjects were interviewed from the INMOL hospital and Sheikh Zayed Hospital, Lahore. The information was collected regarding the characteristics like age, gender, family history of thyroid cancer, use of iodine-diet, radiation therapy, etc. Descriptive and inferential statistics were used to explore the risk factors of the thyroid cancer. Odds ratio and 95% confidence interval (CI) were computed by using logistic regression model. The result showed that the odds ratio and 95% CI for family history of cancer are 2.222 and (1.281-3.853), for use of iodine diet are 2.619 and (1.492-4.596), for acromegaly disease are 1.947 and (1.123-3.374), for oxidative stress are 6.229 and (3.473-11.172), for red meat are 2.601 and (1.421-4.762), for fast food are 3.177 and (1.745-5.785), for fried food are 2.357 and (1.268-4.382), for the use of fats are 2.531 and (1.265-5.064) and for sea food are 2.050 and (1.127-3.729), respectively. It can be concluded that oxidative stress has 6 times high risk of thyroid cancer with the odd ratio 6.229 and CI (3.473, 11.172). Moreover, fast food, the use of iodine diet, red meat and the seafood are also increased the risk factor of thyroid cancer.