Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/13499
Title: PHARMACEUTICAL EQUIVALENCE OF DIFFERENT BRANDS OF OXYTETRACYCLINE USED IN VETERINARY PRACTICE IN PAKISTAN
Authors: Hina, S
Ashraf, M
Rasheed, M.A
Anjum, A.A
Keywords: Oxytetracycline
Chemical equivalence
HPLC
Short acting
Long acting
PVPs
Issue Date: 28-Jan-2018
Publisher: Lahore:Pakistan Association for the Advancement of Science
Citation: Shamsuzzaman, M. M., & Biswas, T. K. (2012). Aqua chemicals in shrimp farm: a study from south-west coast of Bangladesh. The Egyptian Journal of Aquatic Research, 38(4), 275-285.
Abstract: Oxytetracycline is a broad-spectrum antibiotic frequently used in veterinary practice against many infectious diseases. The present study was designed to evaluate the pharmaceutical equivalence of various short acting, PVP and long acting brands of oxytetracycline hydrochloride available in market through HPLC. Dilutions of all the drugs were prepared in acetonitrile and 0.15M sodium acetate (1:1) to obtain final concentrations of 100, 50, 25, 10,1.0 ,0.5, 0.1, and 0.05µg per ml. C-18 column was used and mobile phase was the mixture of 0.15 M sodium acetate and acetonitrile (50:50 v/v). Injection volume was 20µl and flow rate was 1ml/minute. The Limits of detection and quantification calculated were 0.100(µg/ml) and 0.5(µg/ml) respectively. The acceptable percentage value of assay was 90-120%. The concentration of active ingredient (Oxytetracycline hydrochloride) in all preparations was in range except Terrasym PVP-100 (81%) and Onyx-LA (72%).
URI: http://142.54.178.187:9060/xmlui/handle/123456789/13499
Appears in Collections:38th All Pakistan Science Conference "Energy Crisis and their Solution in Pakistan"

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