ASSOCIATION BETWEEN DRD2 GENE POLYMORPHISM AND AGGRESSION AMONG CONVICTED PRISONERS

Abstract

There is an alarming rise of aggression among Pakistani population, especially among teenage. There are various neurotransmitters which are responsible for extreme aggressive behavior. Dopamine receptors have vital role in behavior. Dopamine receptors polymorphism is association with aggressive and violent behavior in man. D2 receptor (DRD2) polymorphisms were examined in convicted persons (n= 10) and normal (n= 10) human samples. Our preliminary results suggest that three polymorphisms in DRD2 are associated with childhood aggression. Future studies are required to replicate the curzrent results and to further explore the relationship between the dopamine system and aggressive behavior in prisoners.