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Title: | Less disease severity of COVID-19 among smokers: An indication of investigating nicotine as preventive measure |
Authors: | Ghayyur, Aysha Hussain, Syed Shahzad Salam, Emaan Saeed, Subhan Shahid, Saman Tanvir Us Salaam |
Keywords: | COVID-19 infection nicotine nitric oxide (NO) cigarette smoking fatality rate |
Issue Date: | 16-Jan-2021 |
Publisher: | Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi |
Abstract: | The study was aimed to mention the epidemiology of smoking in Pakistani COVID-19 infected patients along with the disease severity, oxygen dependency and fatality rate. A cross sectional epidemiological study was carried out on 555 confirmed cases of COVID-19 infection. The median age was 47±16 years. 59% were male and 41% were female. Most of the patients (97.5%) survived, while only 2.5% expired. 25.6% patients required the oxygen. Total 17 (3%) COVID-19 patients with age 20-75 years were identified as smokers. No mortality was observed in smokers. The 1.4% smokers presented with mild disease, 1.2% with moderate disease and 0.4% had severe disease. According to ChiSquare test, there existed an insignificant difference (p- value: 0.38649) between smokers and non-smokers in disease severity levels. Smoking is a precursor for countless diseases, but it behaved differently in COVID-19 infected patients, as its prevalence was significantly low. We found no significant variation of the disease severity among the smokers and non-smokers. Profound experiments should be conducted to recommend whether nicotine can be used as a protective agent to negate COVID-19 infection. |
URI: | http://142.54.178.187:9060/xmlui/handle/123456789/13584 |
ISSN: | 1011-601X |
Appears in Collections: | Issue 01 (Supplementary) |
Files in This Item:
File | Description | Size | Format | |
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15-SUP-1657.htm | 148 B | HTML | View/Open |
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