Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/13584
Title: Less disease severity of COVID-19 among smokers: An indication of investigating nicotine as preventive measure
Authors: Ghayyur, Aysha
Hussain, Syed Shahzad
Salam, Emaan
Saeed, Subhan
Shahid, Saman
Tanvir Us Salaam
Keywords: COVID-19 infection
nicotine
nitric oxide (NO)
cigarette smoking
fatality rate
Issue Date: 16-Jan-2021
Publisher: Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi
Abstract: The study was aimed to mention the epidemiology of smoking in Pakistani COVID-19 infected patients along with the disease severity, oxygen dependency and fatality rate. A cross sectional epidemiological study was carried out on 555 confirmed cases of COVID-19 infection. The median age was 47±16 years. 59% were male and 41% were female. Most of the patients (97.5%) survived, while only 2.5% expired. 25.6% patients required the oxygen. Total 17 (3%) COVID-19 patients with age 20-75 years were identified as smokers. No mortality was observed in smokers. The 1.4% smokers presented with mild disease, 1.2% with moderate disease and 0.4% had severe disease. According to ChiSquare test, there existed an insignificant difference (p- value: 0.38649) between smokers and non-smokers in disease severity levels. Smoking is a precursor for countless diseases, but it behaved differently in COVID-19 infected patients, as its prevalence was significantly low. We found no significant variation of the disease severity among the smokers and non-smokers. Profound experiments should be conducted to recommend whether nicotine can be used as a protective agent to negate COVID-19 infection.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/13584
ISSN: 1011-601X
Appears in Collections:Issue 01 (Supplementary)

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