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Title: | Comparatively the Physiological and Biochemical Changes in Diabetic and Non Diabetic Individuals with Decrease Na+ /K + - Atpase Activity |
Authors: | ASLAM, SAAD MIRZA, RUKHSANA MALIK, FAROOQ AHMAD |
Keywords: | HbA1c, Sodium-Potassium adenosine triphosphatase Reactive oxygen species |
Issue Date: | Dec-2017 |
Publisher: | Pakistan Journal of Medical and Health Sciences |
Citation: | Aslam, S., Mirza, R., & Malik, F. A. (2017). Comparatively the Physiological and Biochemical Changes in Diabetic and Non Diabetic Individuals with Decrease Na+/K+-Atpase Activity. Biochem. Biophys. Acta, 694, 27-68. |
Abstract: | This study was conducted to identify the complications of decreased Na+/K+ATPase activity in the diabetic patients with type 2. This study was conducted in Jinnah Hospital Lahore according to its results the diabetic patients of type2 showed a significant (<0.05) increase in HbA1c levels (7.2±3.2) as compared with control (4.3±0.6). It was concluded that hyperglycemic patients with diabetes type 2 has decreased activity of Na+ /K +ATPase (254±88) as compared to the healthy individuals (387±12). The results of this study indicated that high concentration of glycosylated hemoglobin decreases the activity of Na+ /K +ATPase in diabetic individuals as compared to the control. All the results of this study were significant (<0.05). |
URI: | http://142.54.178.187:9060/xmlui/handle/123456789/13607 |
ISSN: | 1996-7195 |
Appears in Collections: | Oct-Dec,2017,Issue(4) |
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