CYTOTOXIC AND ANALGESIC POTENTIALS OF PAPAVER PAVONINUM FISCH & MEY

Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/13626

Title:	CYTOTOXIC AND ANALGESIC POTENTIALS OF PAPAVER PAVONINUM FISCH & MEY
Authors:	IBRAR, MUHAMMAD EHSAN, MARYAM BARKATULLAH, BARKATULLAH BAHADAR MARWAT, KHAN SARAH MUBARAK, SYEDA
Keywords:	Papaver pavoninum Ethanolic extract Cytotoxicity Analgesic activity
Issue Date:	6-Nov-2015
Publisher:	Karachi: Pakistan Botanical Society, University of Karachi
Citation:	IBRAR¹, M. U. H. A. M. M. A. D., EHSAN¹, M. A. R. Y. A. M., BARKATULLAH¹, K. B., & MUBARAK¹, S. S. (2015). Cytotoxic and analgesic potentials of Papaver pavoninum Fisch & Mey. Pak. J. Bot, 47(5), 1895-1899.
Abstract:	Ethanolic extract of whole plant of Papaver pavoninum was used to investigate its cytotoxic and analgesic potentials. Brine Shrimp Cytotoxic bioassay showed that 100 and 1000 µg/ml doses produced highly significant cytotoxicities causing 83.3±1.924% and 96.7±1.924% lethalities respectively, with LD50 value of 2.54μg/ml. The analgesic bioassay, using acetic acid induced writhing behavior in mice showed that all the three doses of the extract (50, 100 and 150 mg/kg) were highly effective and even more effective than the standard analgesic drug (Diclofenic Sodium), which reduced the number of writhes by 13.54%, while the three doses of the plant extract reduced the writhing by 36.91%, 57.01% and 68.39% respectively
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/13626
ISSN:	2070-3368
Appears in Collections:	2006,Part-1

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