Prevalence of Endometrial Carcinoma in Post-menopausal Bleeding Women

Abstract

Aim: To determine the prevalence of endometrial carcinoma in postmenopausal bleeding women and also examine the accuracy of color Doppler ultrasound for diagnosing the malignant disorder. Method: This observational cross-sectional study was conducted at Department of Gynecology & Obstetrics, Sandeman Provincial Hospital Quetta from 1st January 2017 to 30th September 2018. One hundred and forty women ages ranged from 40 to 80 years whom had irregular vaginal bleeding (postmenopausal bleeding) were included. Patient’s detailed medical history also including age, residency, and education level was noted after taking informed written consent from all the patients. Endometrial thickness, uterine artery resistive index and results of Color Doppler ultrasound were recorded. Results: Thirty nine (27.86%) patients were aged between 40 to 55 years, 76(54.29%) had ages 56 to 70 years and rest 25 (17.85%) patients were aged above than 71 years. 65(46.43%) had urban area residency while 75(53.57%) had rural residency. Fifty eight (41.43%) were literate while 58.57% were illiterate. We found 23(16.43%) patients had endometrial carcinoma while 117 patients had no endometrial carcinoma by Doppler ultrasound. On Doppler ultrasound findings, sensitivity 76.66%, specificity 92.78%, PPV 53.49% and NPV 92.78%. Conclusion: The prevalence of endometrial carcinoma in post-menopausal bleeding women is high and the use of Color Doppler ultrasound for diagnosing endometrial carcinoma in affected women shows effectiveness with better specificity and sensitivity.-+*