Correlation between serum vitamin D expression and changes of immune indexes in children with pneumonia of different degrees

Abstract

To explore the correlation between serum vitamin D expression and changes in immune indicators in children with different degrees of pneumonia. From January 2019 to January 2020, 60 children with pneumonia admitted to our hospital and 30 healthy children who came to our hospital for physical examination were selected as the research subjects, and divided into the severe group (severe pneumonia) and the mild group (mild pneumonia), each 30 cases, and 30 healthy children were set as control group. The serum vitamin D level was observed and detected, and its correlation with humoral and cellular immune indicators were analyzed. Remarkably better results was observed in the control group than the other groups in terms of rate of serum vitamin D deficiency, humoral immunity indexes, cellular immune indexes, the CRP index and the IL-6 index (all p<0.05). Vitamin D expression is positively correlated with immune indexes. There is a certain correlation between serum vitamin D expression and immune indicators. Insufficient serum vitamin D expression gives rise to decreased immune function indicators. Taken together, early detection of children's vitamin D indicators is conducive to understand the severity of the child's condition, and beneficial for the later treatment as well.