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http://142.54.178.187:9060/xmlui/handle/123456789/13884| Title: | Analysis of chemical constituents in the extract and rat serum from the chloroform extract of Oxytropis falcata Bunge by HPLC-MS |
| Authors: | Zhang, Dejun Yuan, Wangtao Zhang, Benyin Hong, Eun-Kyung Shi, Ping Yang, Zhanting Zhang, Yuhao Wang, Honglun |
| Keywords: | Oxytropis falcata Bunge chloroform extract rat serum HPLC-MS |
| Issue Date: | 16-Mar-2020 |
| Publisher: | Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi |
| Abstract: | Analysis of the constituents of the chloroform extract of Oxytropis falcata Bunge (CEOF), a traditional Tibetan medicine, in rat’s serum after oral administration, has been performed by HPLC-MS. We have identified 10 compounds in CEOF and 11 bioactive ingredients from rat’s serum after given CEOF. Six bioactive ingredients from rat’s serum are matched with original form of the compounds of CEOF. Other five bioactive ingredients were seemed to be respectively metabolites. HPLC-MS is rapid, sensitive method and suitable for identification of bioactive components absorbed into blood of CEOF providing information for further research of pharmacological mechanism. |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/13884 |
| ISSN: | 1011-601X |
| Appears in Collections: | Issue 2 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Paper-23.htm | 131 B | HTML | View/Open |
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