Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/13884
Title: Analysis of chemical constituents in the extract and rat serum from the chloroform extract of Oxytropis falcata Bunge by HPLC-MS
Authors: Zhang, Dejun
Yuan, Wangtao
Zhang, Benyin
Hong, Eun-Kyung
Shi, Ping
Yang, Zhanting
Zhang, Yuhao
Wang, Honglun
Keywords: Oxytropis falcata Bunge
chloroform extract
rat serum
HPLC-MS
Issue Date: 16-Mar-2020
Publisher: Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi
Abstract: Analysis of the constituents of the chloroform extract of Oxytropis falcata Bunge (CEOF), a traditional Tibetan medicine, in rat’s serum after oral administration, has been performed by HPLC-MS. We have identified 10 compounds in CEOF and 11 bioactive ingredients from rat’s serum after given CEOF. Six bioactive ingredients from rat’s serum are matched with original form of the compounds of CEOF. Other five bioactive ingredients were seemed to be respectively metabolites. HPLC-MS is rapid, sensitive method and suitable for identification of bioactive components absorbed into blood of CEOF providing information for further research of pharmacological mechanism.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/13884
ISSN: 1011-601X
Appears in Collections:Issue 2

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