Analgesic effect of flurbiprofen axetil in treatment of single hole thoracoscopic surgery for pneumothorax

Abstract

The stress response induced by surgery and anesthesia can inhibit the immune function of the body. Studies have shown that pain can inhibit the proliferation of T cells and weaken the activity of NK cells, resulting in immunosuppression. In this study, flurbiprofen axetil was used for drug intervention. The results showed that flurbiprofen can make the serum TNF- and IL-6 levels significantly reduce, illustrate the application of flurbiprofen axetil can promote the inflammatory balance, inhibit excessive stress reaction, thus contributing to the clinical curative effect and postoperative recovery of patients. The authors have also analyzed treatment of primary spontaneous pneumothorax by using single port thoracoscopy. Based on the analysis of the effect of single hole thoracoscopic surgery, it shows that the average time of single hole thoracoscopic surgery group (49±12.34) min, intraoperative blood loss (32.5±7.32) ml, there was no significant difference between the two groups. The result proved that the technique of single hole thoracoscopic surgery can reduce the injury of the chest wall and the hemostasis time, and reduce the incision scar.