Analgesic effect of different dosage of Flurbiprofen axetil in laparoscopic cholecystectomy in comparison with other analgesic drugs

Abstract

Flurbiprofen axetil is a non-selective cyclooxygenase inhibitor. It can target the aggregation with lipid micro sphere as drug carrier, and exert analgesic effect in surgical incision and inflammatory site. In laparoscopic cholecystectomy comparative study on analgesic effect of parecoxib and flurbiprofen axetil is relatively less. Therefore, this paper is mainly based on the observation of patients after resting VAS score, adverse reaction time and movement, to evaluate the analgesic effect of different drug dose of flurbiprofen and parecoxib sodium, which provides reference for clinical medication. The results show that the intravenous injection of parecoxib could provide effective analgesic effect in laparoscopic cholecystectomy. Also, compared with flurbiprofen, parecoxib shows a more significant analgesic effect.