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Please use this identifier to cite or link to this item: http://142.54.178.187:9060/xmlui/handle/123456789/14155
Title: ASSESSMENT OF ANTICOAGULANT EFFECT OF EVENING PRIMROSE OIL
Authors: RIAZ, AZRA
ALAM KHAN, RAFEEQ
PARVEEN AHMED, SHAHIDA
Keywords: Evening primrose oil
Thrombin time
Prothrombin time
activated partial thromboplastin time
Fibrinogen time
Issue Date: 22-Oct-2009
Publisher: Karachi: Faculty of Pharmacy, University of Karachi
Citation: Riaz, A., Khan, R. A., & Ahmed, S. P. (2009). Assessment of anticoagulant effect of evening primrose oil. Pak J Pharm Sci, 22(4), 355-9.
Abstract: Effect of evening primrose oil (EPO) was assessed on coagulation parameters following 30 and 60 days administration of 90, 180 and 360 µl/kg oil to healthy rabbits of either sex. There was significant increase in all assays except Fibrinogen time. These effects might be due to inactivation or inhibition of factors affecting coagulation. The intake of evening primrose oil also significantly decreased platelet count. Results of this study suggest that evening primrose oil shows considerable anti-anticoagulant and anti-platelet activity in animals and has potential to reduce cardiovascular morbidity and mortality.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/14155
ISSN: 1011-601X
Appears in Collections:Issue 04

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