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  8. Volume 21
  9. Issue 3
Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/14167
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dc.contributor.authorBASHIR, SAJID-
dc.contributor.authorJAMSHAID, MOHAMMAD-
dc.contributor.authorAHMAD, BASHIR-
dc.contributor.authorIQBAL, JAVEID-
dc.date.accessioned2022-11-29T05:07:50Z-
dc.date.available2022-11-29T05:07:50Z-
dc.date.issued2008-07-04-
dc.identifier.citationBashir, S., Jamshaid, M., Ahmad, B., & Iqbal, J. (2008). Pharmacokinetics of ciprofloxacin in normal rabbits and changes observed in induced dehydrated state. Pakistan Journal of Pharmaceutical Sciences, 21(3), 225-230.en_US
dc.identifier.issn1011-601X-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/14167-
dc.description.abstractThe pharmacokinetics of ciprofloxacin following oral administration of a single dose of 20mg/Kg body weight was investigated in normal rabbits and changes were observed in water-deprived rabbits. High performance liquid chromatographic method was employed for the determination of plasma concentration of ciprofloxacin. The mean plasma concentration and AUC (0-t) and AUC (0-inf) were significantly different between normal and dehydrated rabbits (P<0.05), but the absorption rate, distribution rate, and elimination rate did not show any statistically significant difference. The results reflect a need for monitoring toxicity of ciprofloxacin in the water-deprived condition.en_US
dc.language.isoenen_US
dc.publisherKarachi:Pakistan Journal of Botany, Botanical Garden, University of Karachien_US
dc.subjectPharmacokineticsen_US
dc.subjectciprofloxacinen_US
dc.subjectplasma concentrationen_US
dc.subjectdehydrated rabbitsen_US
dc.titlePHARMACOKINETICS OF CIPROFLOXACIN IN NORMAL RABBITS AND CHANGES OBSERVED IN INDUCED DEHYDRATED STATEen_US
dc.typeArticleen_US
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