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http://142.54.178.187:9060/xmlui/handle/123456789/14219| Title: | FORMULATION AND EVALUATION OF CETIRIZINE DIHYDROCHLORIDE ORODISPERSIBLE TABLET |
| Authors: | SUBRAMANIAN, S SANKAR, V MANAKADAN, ASHA ASOKAN ISMAIL, SAREENA ANDHUVAN, G |
| Keywords: | Cetirizine orodispersible tablets HPLC method hausner ratio wetting time |
| Issue Date: | 19-Apr-2010 |
| Publisher: | Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi |
| Citation: | Subramanian, S., Sankar, V., Manakadan, A. A., Ismail, S., & Andhuvan, G. (2010). Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet. Pakistan journal of pharmaceutical sciences, 23(2), 232-236. |
| Abstract: | Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulation CZ2 (1:1:3). The hardness and friability of all the formulations were found to be within the standard limit for orodispersible tablets. Disintegration time was found to be rapid in formulation CZ2 (1:1:3).The in vitro dissolution time was found to be 100% in 11 minutes for the formulation CZ2 (1:1:3). |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/14219 |
| ISSN: | 1011-601X |
| Appears in Collections: | Issue 02 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Paper-19.htm | 143 B | HTML | View/Open |
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