FORMULATION AND EVALUATION OF CETIRIZINE DIHYDROCHLORIDE ORODISPERSIBLE TABLET

Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/14219

Title:	FORMULATION AND EVALUATION OF CETIRIZINE DIHYDROCHLORIDE ORODISPERSIBLE TABLET
Authors:	SUBRAMANIAN, S SANKAR, V MANAKADAN, ASHA ASOKAN ISMAIL, SAREENA ANDHUVAN, G
Keywords:	Cetirizine orodispersible tablets HPLC method hausner ratio wetting time
Issue Date:	19-Apr-2010
Publisher:	Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi
Citation:	Subramanian, S., Sankar, V., Manakadan, A. A., Ismail, S., & Andhuvan, G. (2010). Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet. Pakistan journal of pharmaceutical sciences, 23(2), 232-236.
Abstract:	Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulation CZ2 (1:1:3). The hardness and friability of all the formulations were found to be within the standard limit for orodispersible tablets. Disintegration time was found to be rapid in formulation CZ2 (1:1:3).The in vitro dissolution time was found to be 100% in 11 minutes for the formulation CZ2 (1:1:3).
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/14219
ISSN:	1011-601X
Appears in Collections:	Issue 02

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