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dc.contributor.authorBALAJI, S-
dc.contributor.authorSUNITHA, A-
dc.date.accessioned2022-11-30T09:09:33Z-
dc.date.available2022-11-30T09:09:33Z-
dc.date.issued2010-10-04-
dc.identifier.citationBalaji, S., & Sunitha, A. (2010). Development and validation of spectrophotometeric method for simultaneous determination of simvastatin and ezetimibe in tablet formulations. Pakistan Journal of Pharmaceutical Sciences, 23(4), 375-379.en_US
dc.identifier.issn1011-601X-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/14259-
dc.description.abstractA versatile, accurate, precise and economic method for simultaneous determination of simvastatin and ezetimibe in fixed dose combination products was developed. The absorbance values at 236 nm and 234 nm of over line spectrum was used for the estimation of simvastatin and ezetimibe, respectively without mutual interference. This method obeyed Beer’s law in the concentration range of 4 – 16 µg /ml for simvastatin and 4- 16 µg /ml for ezetimibe. The results of analyses have been validated statistically for linearity, accuracy and precision of the proposed method.en_US
dc.language.isoenen_US
dc.publisherKarachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachien_US
dc.subjectSimvastatin (SMV)en_US
dc.subjectEzetimibe (EZE)en_US
dc.subjectmethanolen_US
dc.subjectultraviolet spectrophotometryen_US
dc.subjectabsorption ratio methoden_US
dc.titleDEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETERIC METHOD FOR SIMULTANEOUS DETERMINATION OF SIMVASTATIN AND EZETIMIBE IN TABLET FORMULATIONSen_US
dc.typeArticleen_US
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