Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/14274
Title: PRUNES AND LIVER FUNCTION: A CLINICAL TRIAL
Authors: AHMED, TALAT
SADIA, HALIMA
KHALID, ANEELA
BATOOL, SADIA
JANJUA, AYESHA
Keywords: Prunus domestica
Serum Alkaline Phosphatase
Serum Alanine Transaminase
Serum Aspartate Transaminase and Bilirubin
Issue Date: 19-Oct-2010
Publisher: Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi
Citation: Ahmed, T., Sadia, H., Khalid, A., Batool, S., & Janjua, A. (2010). Prunes and liver function: a clinical trial. Pakistan Journal of Pharmaceutical Sciences, 23(4), 463-467.
Abstract: Prunes are used by folks as a remedy of various diseases including hepatitis. A clinical trial was designed to see the effects of prunes (Prunus domestica) on liver function. 166 healthy volunteers were divided into three groups randomly. Either three (about11.43g) or six (23g approx.) prunes were soaked in a glass of water (250ml) overnight. Each subject from two test groups was asked to drink prune juice & eat whole fruit(single or double dose of prunes) as well, early in the morning, daily for 8 weeks; whereas each subject from control group was given a glass of water to drink. Blood samples were taken at week 0 and week 8 for chemical analysis. There was significant reduction of serum alanine transaminase (p 0.048) and serum alkaline phosphatase (p 0.017) by the lower dose of prunes. There was no change in serum aspartate transaminase and bilirubin. Alteration in liver function by use of prunes may have clinical relevance in appropriate cases and prunes might prove beneficial in hepatic disease.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/14274
ISSN: 1011-601X
Appears in Collections:Issue 04

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