ANTI-EMETIC ACTIVITY OF SOME LEGUMINOUS PLANTS

Abstract

Crude methanol extracts of the leaves of Adenanthera pavonina L., Peltoforum roxburghii L, Prosopis cineraria L., and Prosopis juliflora DC., were evaluated for anti-emetic activity. Emesis was induced by the oral administration of copper sulphate 50mg/kg body weight to male chicks of four days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. All extracts (150 mg / kg body weight orally) showed anti-emetic activity when compared with standard drug Chlorpromazine at the same dose. Among all the extracts, Prosopis juliflora showed the highest (73.64%) and Adenanthera pavonina showed the lowest (50.17%) anti-emetic activity.