Analysis of the advantages and disadvantages in application of oxygendriven aerosol and aerosol inhalation by air compressor for the pediatric asthma

Abstract

Present study is done to analyze the advantages and disadvantages in application of oxygen-driven aerosol and aerosol inhalation by air compressor for the pediatric asthma. A total of 180 patients with pediatric bronchial asthma were randomized into the oxygen-driven aerosol group (Group A, n=90) and the air compressor-driven aerosol group (Group B, n=90). Patients in both groups received 0.5 mg budesonide suspension, 0.2 mg salbutamol and 4 mL normal saline, and following the treatment, we recorded the excellence rate, improvement rate, total effectiveness rate, and the changes in oxyhemoglobin saturation (SaO2) before and after treatment, and the remission time in two groups. In Group A, patients had a higher total effectiveness rate (95.79% vs. 75.79%) but a lower failure rate (4.21% vs. 24.21%) than those in the Group B, with statistically significant differences (p>0.05). Following the aerosol inhalation, SaO2 levels in two groups were ameliorated in comparison with the levels before treatment [Group A: (95.4±0.4) % vs. (80.6±0.8%, Group B: (92.1±1.1)% vs. (79.3±0.7)%] (p<0.05), and the level in Group A following the treatment was higher than that in Group B [(95.4±0.4) % vs. (92.1±1.1)%] (p<0.05). Furthermore, patients in Group A had a longer effective remission time and total remission time than those in Group B, but the differences had no statistical significance (p>0.05). Both of the oxygen-driven aerosol inhalation and aerosol inhalation by air compressor can improve the clinical symptoms of pediatric asthma effectively, but oxygen-driven aerosol inhalation works more efficiently, with an elevated SaO2. Thus, oxygen-driven aerosol inhalation is preferred in clinical practice.