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http://142.54.178.187:9060/xmlui/handle/123456789/15131| Title: | Biologically active compounds from the red sea sponge Suberea sp. |
| Authors: | Shaala, Lamiaa A Almohammadi, Ameen |
| Keywords: | Red Sea sponge Suberea species pyrrole derivatives phenolic and halogenated compounds cytotoxic and antimicrobial activities. |
| Issue Date: | 10-Nov-2017 |
| Publisher: | Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
| Citation: | Shaala, Lamiaa A., and Ameen Almohammadi. "Biologically active compounds from the red sea sponge Suberea sp." Pak. J. Pharm. Sci 30, no. 6 (2017): 2389-2392. |
| Abstract: | Investigation of the cytotoxic fraction of the extracts of the Red Sea sponge Suberea sp. resulted in the identification of two new compounds, 1-(hydroxy(1H-pyrrol-2-yl)methyl)guanidine and 4-(2-amino-3-methylbut-3-en-1-yl)phenol (1 and 2) together with the previously reported 2-(3,5-dibromo-4-hydroxyphenyl)acetamide (3), subereaphenol C (4), dibromoverongiaquinol (5) and bromochloroverongiaquinol (6). The compounds were assigned by interpretation of their one- and two-dimensional NMR and MS spectral data. The cytotoxic activities of the compounds against two cancer cell lines were evaluated. In addition, the antimicrobial activities of the compounds were discussed. |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/15131 |
| ISSN: | 1011-601X |
| Appears in Collections: | No.6 (Supplementary), November 2017 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 10-SUP-755.htm | 147 B | HTML | View/Open |
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