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Title: | In vitro activity of antimicrobial agents against streptococcus pyogenes isolated from different regions of Khyber Pakhtun Khwa Pakistan |
Authors: | Rizwan, Muhammad Bakht, Jehan Bacha, Nafees Ahmad, Bashir |
Keywords: | S. pyogenes. Hemolysis GAS, rheumatic fever pharyngitis Pyrrolidonyl arylmidase (PYR) |
Issue Date: | 20-Jan-2016 |
Publisher: | Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. |
Citation: | Rizwan, M., Bakht, J., Bacha, N., & Ahmad, B. (2016). In vitro activity of antimicrobial agents against streptococcus pyogenes isolated from different regions of Khyber Pakhtun Khwa Pakistan. Pakistan journal of pharmaceutical sciences, 29(1). |
Abstract: | The present study investigates the antibiotic resistance of S. pyogenes of 600 isolates collected from different body parts including throat and sputum were analyzed for their antimicrobial susceptibility to 5 antibiotics using the Kirby Bauer disc diffusion method. Based on different identification tests including, gram staining, beta hemolysis, catalase test and bacitracin sensitivity test, a total of 138 isolates were confirmed as S. pyogenes. The prevalence of S. pyogenes was 80% in sore throat and 29% in sputum samples. These isolates were further tested for antibiotics resistance using disk diffusion method. Out of 138 isolates, 49.27% isolates showed resistance towards cefixime, 28.98% towards cefotaxime and 17.39% towards ciprofloxacin, 17.39% towards ampicillin, 17.39% towards erythromycin, 15.94% towards streptomycin, 0.724% isolates towards chloromphenicol and 0% towards penicillin. Among the resistant isolates of S. pyogenes, 60.71% showed resistance towards cefixime, 57.14% towards ciprofloxacin, 57.14% towards streptomycin, 50% towards erythromycin and 25% towards cefotaxime |
URI: | http://142.54.178.187:9060/xmlui/handle/123456789/15152 |
ISSN: | 1011-601X |
Appears in Collections: | Issue 01 |
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