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http://142.54.178.187:9060/xmlui/handle/123456789/15158| Title: | Analgesic activity of alkyl piperidine derivatives |
| Authors: | Jahan, Sarwat Akhtar, Shamim Kamil, Arfa Mushtaq, Nousheen Saify, Zafar Saied Arif, Muhammad |
| Keywords: | Alkyl piperidine derivatives analgesic activity SAR. |
| Issue Date: | 20-Jan-2016 |
| Publisher: | Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. |
| Citation: | Jahan, S., Akhtar, S., Kamil, A., Mushtaq, N., Saify, Z. S., & Arif, M. (2016). Analgesic activity of alkyl piperidine derivatives. Pakistan journal of pharmaceutical sciences, 29(1). |
| Abstract: | Piperidine is the most significant scaffold which reveals therapeutic potential because of its conformationally flexible nature. During the course of present investigations synthetic quaternary salts of alkyl piperidine with various phenacyl bromides were explored for their possible analgesic activity. Compounds I analogs (1a-1f) and compound II analogs (IIa-IIf) showed varying degree of analgesic activity when compared with pethidine as standard and its duration by tail immersion method. |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/15158 |
| ISSN: | 1011-601X |
| Appears in Collections: | Issue 01 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Paper-10.htm | 132 B | HTML | View/Open |
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