Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/15187
Title: Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability
Authors: Waqas, Muhammad Khurram
Akhtar, Naveed
Akhtar Shah, Pervaiz
Zeeshan, Muhammad
Ali Shah, Arshad
Braga, Valdir de Andrade
Ali Khan, Barkat
Keywords: Grape seed extract
w/o Emulsion, stability
pH, electrical conductivity
rheology
Issue Date: 20-Jan-2016
Publisher: Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi.
Citation: Waqas, M. K., Akhtar, N., Shah, P. A., Danish, M. Z., Shah, A. A., de Andrade Braga, V., & Khan, B. A. (2016). Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability. Pakistan Journal of Pharmaceutical Sciences, 29(1).
Abstract: The aim of current research was to develop a water-in-oil emulsion containing grape seed extract for application in cosmeceuticals. Finally grinded dried grape seeds powder was extracted with hydro alcoholic mixture. Emulsions consisting of different concentrations of cetyl dimethicone (Abile EM90), the nonionic emulsifier, liquid paraffin as oily phase and water as aqueous phase were developed. Color, odor, pH, viscosity, liquefaction, phase separation, centrifugation and thermal stability of the formulated emulsions were observed at various storage temperatures i.e. 8±0.5°C, 25±0.5°C, 40±0.5°C and 40°C±0.5°C with 70% RH. The stable formulation consist of 16% mineral oil, 4% of ABIL EM 90®, 4% grape seeds extract, 1% rose oil and 75% distilled water. All the results derived from this study showed good stability over the three months study period which indicates w/o emulsion can be used as carrier of 4% grape seeds extract to enhance desired effects when applied topically.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/15187
ISSN: 1011-601X
Appears in Collections:Issue 01

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