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Title: | Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability |
Authors: | Waqas, Muhammad Khurram Akhtar, Naveed Akhtar Shah, Pervaiz Zeeshan, Muhammad Ali Shah, Arshad Braga, Valdir de Andrade Ali Khan, Barkat |
Keywords: | Grape seed extract w/o Emulsion, stability pH, electrical conductivity rheology |
Issue Date: | 20-Jan-2016 |
Publisher: | Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. |
Citation: | Waqas, M. K., Akhtar, N., Shah, P. A., Danish, M. Z., Shah, A. A., de Andrade Braga, V., & Khan, B. A. (2016). Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability. Pakistan Journal of Pharmaceutical Sciences, 29(1). |
Abstract: | The aim of current research was to develop a water-in-oil emulsion containing grape seed extract for application in cosmeceuticals. Finally grinded dried grape seeds powder was extracted with hydro alcoholic mixture. Emulsions consisting of different concentrations of cetyl dimethicone (Abile EM90), the nonionic emulsifier, liquid paraffin as oily phase and water as aqueous phase were developed. Color, odor, pH, viscosity, liquefaction, phase separation, centrifugation and thermal stability of the formulated emulsions were observed at various storage temperatures i.e. 8±0.5°C, 25±0.5°C, 40±0.5°C and 40°C±0.5°C with 70% RH. The stable formulation consist of 16% mineral oil, 4% of ABIL EM 90®, 4% grape seeds extract, 1% rose oil and 75% distilled water. All the results derived from this study showed good stability over the three months study period which indicates w/o emulsion can be used as carrier of 4% grape seeds extract to enhance desired effects when applied topically. |
URI: | http://142.54.178.187:9060/xmlui/handle/123456789/15187 |
ISSN: | 1011-601X |
Appears in Collections: | Issue 01 |
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