Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/15728
Title: NEW PERSPECTIVE OF DENDROBIUM CRUMENATUM ORCHID FOR ANTIMICROBIAL ACTIVITY AGAINST SELECTED PATHOGENIC BACTERIA
Authors: SANDRASAGARAN, UMA MAGESWARY
SUBRAMANIAM, SREERAMANAN
MURUGAIYAH, VIKNESWARAN
Issue Date: 15-May-2014
Publisher: Karachi: Pakistan Botanical Society
Citation: Sandrasagaran, U. M., Subramaniam, S., & Murugaiyah, V. I. K. N. E. S. W. A. R. A. N. (2014). New perspective of Dendrobium crumenatum orchid for antimicrobial activity against selected pathogenic bacteria. Pak. J. Bot, 46(2), 719-724.
Abstract: The present study was undertaken to investigate the potential anti-microbial activity from different parts of Dendrobium crumenatum (leaf, stem, root and pseudo-bulb) against 8 pathogenic bacteria. The antimicrobial activities were determined by using disc diffusion assay, microdilution test for determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The methanolic extracts of stem, root and pseudo-bulb displayed antimicrobial activity comparable to that of the standard antibiotics. Stem extract of D. crumenatum had the most potent antimicrobial activity against Staphylococcus aureus, Klebsiella pneumoniae and Enterobacter aerogenes with MIC values of 0.39, 0.195 and 0.195mg/mL, respectively. Root and stem extracts were found to be active against Streptococcus pneumoniae, Shigella dysentriae and Saccharomyces cerevisiae with MIC values of 0.78 mg/ml compared to 0.00312mg/mL, 0.025mg/mL and 0.0125mg/mL of standard antibiotics of amoxcillin, chloramphenicol and kanamycin. Stem and root extracts yield MBC values in the range of 0.78 mg/mL to 6.25 mg/mL against Staphylococcus aureus, Enterobacter aerogenes, Klebsiella pneumoniae and Saccharomyces cerevisiae. The present study showed that D. crumenatum exhibited potential antimicrobial activity which could be due to the presence of alkaloid and flavonoid compounds and this is a first report on South East Asia region’s wild orchid.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/15728
ISSN: 2070-3368
Appears in Collections:Issue 02

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