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http://142.54.178.187:9060/xmlui/handle/123456789/15909| Title: | The anemonin content of four different Ranunculus species |
| Authors: | Neag, Teodora Olah, Neli-Kinga Hanganu, Daniela Benedec, Daniela Pripon, Flavia Furtuna Ardelean, Aurel Toma, Claudia Crina |
| Keywords: | Ranunculus ficaria Ranunculus bulbosus Ranunculus sardous Ranunculus sceleratus TLC HPLC-DAD anemonin |
| Issue Date: | 1-Sep-2018 |
| Publisher: | Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
| Citation: | Neag, T., Olah, N. K., Hanganu, D., Benedec, D., Pripon, F. F., Ardelean, A., & Toma, C. C. (2018). The anemonin content of four different Ranunculus species. Pakistan Journal of Pharmaceutical Sciences. |
| Abstract: | The Ranunculus species are poorly known as medicinal plants. They have potential toxicity given by the ranunculin and its enzymatic degradation compounds: protoanemonin and anemonin. This paper aims to evaluate the anemonin content of four species: R. bulbosus, R. ficaria, R. sardous and R. sceleratus. The evaluation was performed by TLC and HPLC. There were evaluated two types of extracts hydroalcoholic (HA) and glycerol-ethanol (GE). The most concentrated extract in anemonin was found to be the R. sardous aerial part HA extract: 2.66 mg/ml. The lowest anemonin content is in R. sceleratus: 0.13-0.19 mg/ml. In R. bulbosus aerial part the anemonin content is less than the used HPLC method detection limits (7.68 mg/ml). In all cases the GE extracts are less concentrated in anemonin, being more safely for human administration. |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/15909 |
| ISSN: | 1011-601X |
| Appears in Collections: | Issue No.5 (Supplementary) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 1-SUP-864.htm | 146 B | HTML | View/Open |
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