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Title: | Total polyphenolic compounds, total flavonoids, GC-MS analysis of volatile constituents, evaluation of antioxidant and antimicrobial activities of Prunus dulcis nuts |
Authors: | Qureshi, Muhammad Nasimullah Numonov, Sodik Haji Akber Aisa |
Keywords: | Prunus dulcis nuts total polyphenolics and flavonoids contents GC-MS antioxidant activity antimicrobial activity |
Issue Date: | 2-Jul-2019 |
Publisher: | Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
Citation: | Qureshi, M. N., Numonov, S., & Aisa, H. A. (2019). Total polyphenolic compounds, total flavonoids, GC-MS analysis of volatile constituents, evaluation of antioxidant and antimicrobial activities of Prunus dulcis nuts. Pakistan Journal of Pharmaceutical Sciences, 32(4), 1461-1466. |
Abstract: | Prunus dulcis has been known as a source of nutrients in many traditional foods and as a source of important biologically active compounds in traditional medicines. The present study describes the determination of total polyphenolic compounds, total flavonoids and GC-MS analysis of hexane and chloroform fractions of 70% ethanol extract of whole almond shelled seed. Antioxidant and antimicrobial activities of various extracts of the nuts were evaluated. Folin-Ciocalteau procedure resulted in total polyphenolic compounds as 0.008 mg (gallic acid equivalents)/mg of the dried extract and amount of total flavonoids contents yielded were 0.001 mg (quercetin equivalents)/mg of the nuts dried extracts. GC-MS analysis of the hexane and chloroform fractions yielded a number of volatile constituents, resulting in highest amounts of 6-Octadecenoic acid and 1,1,3,3-Tetramethyl cyclopentane as 37.52% and 24.54% in hexane and chloroform fractions respectively. Antioxidant activity using the DPPH radical scavenging assay resulted in very low activity in all the extracts. Only n-butanol extract showed mild activity against the gram negative E. coli with inhibition zone diameter 8 mm while rest of samples did not show any activity against any microbial strains under study. |
URI: | http://142.54.178.187:9060/xmlui/handle/123456789/15991 |
ISSN: | 1011-601X |
Appears in Collections: | Issue 4 |
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Paper-2.htm | 130 B | HTML | View/Open |
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