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http://142.54.178.187:9060/xmlui/handle/123456789/16066| Title: | Effects of Costus speciosus ethanolic extract on male rats: The action mechanism and the ability to impregnate |
| Authors: | Sari, Ika Puspita Nurrochmad, Arief Setiawan, Irfan Muris Hertiani, Triana Paramita, Annisa Dian Annisa, Anggit Yustitia |
| Keywords: | Costus extract reproductive hormones obstacles to pregnancy sexual behavior |
| Issue Date: | 5-May-2018 |
| Publisher: | Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
| Citation: | Sari, I. P., Nurrochmad, A., Setiawan, I. M., Hertiani, T., Paramita, A. D., & Annisa, A. Y. (2018). Effects of Costus speciosus ethanolic extract on male rats: The action mechanism and the ability to impregnate. Pakistan Journal of Pharmaceutical Sciences, 31. |
| Abstract: | To examine the action mechanism that mediates the anti-fertility effect of Costus speciosus extract, research was conducted on male Sprague-Dawley rats. Costus extract was given to male rats for 14 days at various doses, namely 275, 550 and 1,100 mg kg-1 day-1 in 0.5% sodium CMC. The results showed that Costus extract with doses ranging from 275 to 1,100 mg kg-1 day-1 was able to inhibit pregnancy among female rats by 10-70%. No obstacles in terms of sexual behavior were identified among male rats. The anti-fertility effect of Costus extract kicked in without involving a decreased level of male reproductive hormones. |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/16066 |
| ISSN: | 1011-601X |
| Appears in Collections: | Issue No.3 (Supplementary) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 5-SUP-839.htm | 146 B | HTML | View/Open |
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