Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/16146
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dc.contributor.authorKiran Rafiq-
dc.contributor.authorSaify, Zafar Saied-
dc.contributor.authorShagufta Nesar-
dc.contributor.authorAmbreen Faiyaz-
dc.contributor.authorMuhammad, Iyad Naeem-
dc.date.accessioned2023-01-20T04:54:12Z-
dc.date.available2023-01-20T04:54:12Z-
dc.date.issued2018-07-20-
dc.identifier.citationRafiq, K., Saify, Z. S., Nesar, S., Faiyaz, A., & Muhammad, I. N. (2018). Some novel piperidine analogues having strong alpha glucosidase inhibition. Pakistan Journal of Pharmaceutical Sciences, 31(4), 1185-1190.en_US
dc.identifier.issn1011-601X-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/16146-
dc.description.abstractThe idea of this study is based on the marvelous fact of nojirimycin and deoxy nojirimycin, naturally occurring from piperidine class and having their role as alpha glucosidase inhibitors. In the present work some hydroxy piperidine analogues have been synthesized and analysed for their hypoglycemic effect through glucosidase inhibition owing to the structural resemblance with nojirimycin. The activity was done by spectral absorbance analysis using acarbose as standard. Two analogues (I & IV) were found to pose excellent activity having 87.4 and 54.7% inhibition respectively, hence strengthening the idea of studying piperidine analogiues as glucosidase inhibitors due to structural similarity with nojirimycin.en_US
dc.language.isoenen_US
dc.publisherKarachi: Pakistan Botanical Society, University of Karachien_US
dc.subjectNojirimycinen_US
dc.subjectPiperidineen_US
dc.subjectAnaloguesen_US
dc.subjecthypoglycemicen_US
dc.subjectglucosidase.en_US
dc.titleSome novel piperidine analogues having strong alpha glucosidase inhibitionen_US
dc.typeArticleen_US
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