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dc.contributor.authorTeng Hong-
dc.contributor.authorHu Min-
dc.contributor.authorZeng Hui-
dc.contributor.authorLiu Yuejian-
dc.contributor.authorYuan Lixing-
dc.contributor.authorLiang, Xie Zheng-
dc.date.accessioned2023-01-20T05:00:35Z-
dc.date.available2023-01-20T05:00:35Z-
dc.date.issued2018-07-20-
dc.identifier.citationHong, T., Min, H., Hui, Z., Yuejian, L., Lixing, Y., & Liang, X. Z. (2018). Oral administration of honokiol attenuates airway inflammation in asthmatic mouse model. Pakistan Journal of Pharmaceutical Sciences, 31(4), 1279-1285.en_US
dc.identifier.issn1011-601X-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/16158-
dc.description.abstractAllergic asthma is a disease that pathologically characterized by eosinophilia infiltration, airway inflammation and hyper responsiveness. In this study, we evaluated the anti-inflammatory and anti-allergy possibilities of honokiol, a bi-phenolic compound obtained from species of the genus Magnolia, which has long been involved in traditional Chinese prescriptions for asthma-related lung diseases, in an ovalbumin-induced mouse model of allergic asthma. We found honokiol significantly inhibited the eosinophilia infiltration, reduced the airway inflammation and suppressed the production of inflammatory cytokines) as well as the IgE in serum. Moreover, MMP-9 and? (IL-4 and IFN- NF-кB were found to be involved in the honokiol induced biological process. These results suggested that honokiol may be a possible candidate in the treatment of lung asthma related diseases.en_US
dc.language.isoenen_US
dc.publisherKarachi: Pakistan Botanical Society, University of Karachien_US
dc.subjectHonokiol, asthmaen_US
dc.subjectanti-allergyen_US
dc.subjectanti-inflammation.en_US
dc.titleOral administration of honokiol attenuates airway inflammation in asthmatic mouse modelen_US
dc.typeArticleen_US
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