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Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/16224
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dc.contributor.authorChen, Xueguo-
dc.date.accessioned2023-01-20T05:54:59Z-
dc.date.available2023-01-20T05:54:59Z-
dc.date.issued2014-09-17-
dc.identifier.citationChen, X. (2014). Simultaneous analysis of cocaine and its metabolites in rat liver microsome s 9 fraction by liquid chromatography-mass spectrometry. Pakistan Journal of Pharmaceutical Sciences, 27(5).en_US
dc.identifier.issn1011-601X-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/16224-
dc.description.abstractA method utilizing liquid chromatography-mass spectrometry for the simultaneous analysis of cocaine and its in-vitro metabolites in rat liver micro some S9 fraction is described. Cocaine was incubated with rat liver micro some S9 fraction firstly, and then the incubation sample mixture was analyzed by liquid chromatography-mass spectrometry in full-scan mode. The main metabolites of cocaine were identified from the determination of molecular ions and the results of tandem mass spectrometry analysis. There were two metabolites were identified in the rat liver S9 fractions referring to the literature reports.en_US
dc.language.isoenen_US
dc.publisherKarachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachien_US
dc.subjectliquid chromatography-mass spectrometryen_US
dc.subjectliver microsomeen_US
dc.subjectcocaineen_US
dc.subjectmetabolismen_US
dc.titleSimultaneous analysis of cocaine and its metabolites in rat liver microsome s9 fraction by liquid chromatography-mass spectrometryen_US
dc.typeArticleen_US
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