Simultaneous analysis of cocaine and its metabolites in rat liver microsome s9 fraction by liquid chromatography-mass spectrometry

Chen, Xueguo

Please use this identifier to cite or link to this item: http://142.54.178.187:9060/xmlui/handle/123456789/16224

Full metadata record

DC Field	Value	Language
dc.contributor.author	Chen, Xueguo	-
dc.date.accessioned	2023-01-20T05:54:59Z	-
dc.date.available	2023-01-20T05:54:59Z	-
dc.date.issued	2014-09-17	-
dc.identifier.citation	Chen, X. (2014). Simultaneous analysis of cocaine and its metabolites in rat liver microsome s 9 fraction by liquid chromatography-mass spectrometry. Pakistan Journal of Pharmaceutical Sciences, 27(5).	en_US
dc.identifier.issn	1011-601X	-
dc.identifier.uri	http://142.54.178.187:9060/xmlui/handle/123456789/16224	-
dc.description.abstract	A method utilizing liquid chromatography-mass spectrometry for the simultaneous analysis of cocaine and its in-vitro metabolites in rat liver micro some S9 fraction is described. Cocaine was incubated with rat liver micro some S9 fraction firstly, and then the incubation sample mixture was analyzed by liquid chromatography-mass spectrometry in full-scan mode. The main metabolites of cocaine were identified from the determination of molecular ions and the results of tandem mass spectrometry analysis. There were two metabolites were identified in the rat liver S9 fractions referring to the literature reports.	en_US
dc.language.iso	en	en_US
dc.publisher	Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi	en_US
dc.subject	liquid chromatography-mass spectrometry	en_US
dc.subject	liver microsome	en_US
dc.subject	cocaine	en_US
dc.subject	metabolism	en_US
dc.title	Simultaneous analysis of cocaine and its metabolites in rat liver microsome s9 fraction by liquid chromatography-mass spectrometry	en_US
dc.type	Article	en_US
Appears in Collections:	Issue No.5 (Supplementary)

Files in This Item:

File	Description	Size	Format
17-SUP-111.htm		147 B	HTML	View/Open

Show simple item record