Comparison of clinical efficacy and safety between articaine and lidocaine in the anaesthesia management of tooth pulp disease

Abstract

To evaluate and compare the clinical efficacy and safety between articaine and lidocaine in the anaesthesia management of tooth pulp disease. The 160 patients with tooth pulp disease treated at our hospital were enrolled. After informed consent was obtained, patients were randomly assigned to study group and control group, with 80 patients in each group. Of those, lidocaine was administered to the control group while articaine was given to the study group. The onset time, analgesic effect and adverse events were recorded. Compared with control group, the onset time was significantly reduced in study group (p<0.05). Patients treated with articaine had better analgesic effect than patients in control group (p<0.05). And the incidence of adverse events was notably lower in study group (p<0.05). Compared with lidocaine, articaine presents higher analgesic efficacy and safety for patients with tooth pulp disease.