Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/16421
Title: DETERMINATION OF TOXIC METALS IN SOME HERBAL DRUGS THROUGH ATOMIC ABSORPTION SPECTROSCOPY
Authors: BUSHRA HINA
RIZWANI, GHAZALA HAFEEZ
SHAHID NASEEM
Keywords: Atomic absorption spectrophotometer
environmental pollution
heavy metal toxicity
herbal drugs
Issue Date: 20-Jul-2011
Publisher: Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi.
Citation: Hina, B., Rizwani, G. H., & Naseem, S. (2011). Determination of toxic metals in some herbal drugs through atomic absorption spectroscopy. Pakistan journal of pharmaceutical sciences, 24(3).
Abstract: This study presents a picture of occurrence of heavy metals (Pb, Cd, Cu, Cr, Co, Fe, Ni, Zn) in some selected valuable herbal drugs (G. glabra, O. bracteatum, V. odorata , F. vulgare, C. cyminum, C. sativum, and Z. officinalis) purchased from three different zones (southern, eastern, and western) of Karachi city using atomic absorption spectrophotometer. Heavy metal concentrations in these drugs were found in the range of: 3.26- 30.46 for Pb, 1.6-4.91 for Cd, 0.65-120.21 for Cu, 83.74-433.76 for Zn, 1.61-186.75 for Cr, 0.48-76.97 for Ni, 5.54-77.97 for Co and 65.68-1652.89 µg/g for Fe. Percentage of heavy metals that were found beyond the permissible limits were: 71.4% for Pb, 28.51% for Cd, 14.2% for Cu, and 9.5 % for Cr. Significant difference was noticed for each heavy metal among herbal drugs as well as their zones of collection using two way ANOVA followed by least significant (LSD) test at p<0.05.Purpose of this research is to detect each type of heavy metal contaminant of herbal drugs by environmental pollution, as well as to highlight the health risks associated with the use of such herbal drugs that contain high levels of toxic heavy metals.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/16421
ISSN: 1011-601X
Appears in Collections:Issue 03

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