ANTIOXIDANT ACTIVITY OF COVOLVULUS HYSTRIX VAHL AND ITS CHEMICAL CONSTITUENTS

Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/16431

Title:	ANTIOXIDANT ACTIVITY OF COVOLVULUS HYSTRIX VAHL AND ITS CHEMICAL CONSTITUENTS
Authors:	DONIA, ABD EL RAHEIM MOHAMMED ALQASOUMI, SALEH IBRAHIM AWAAD, AMANI SHAFEEK CRACKER, LYLE
Keywords:	Antioxidant activity Convolvulus hystrix flavonoids ferulic acid total phenolics
Issue Date:	8-Apr-2011
Publisher:	Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi
Citation:	ABD EL RAHEIM MOHAMMED, D. O. N. I. A., Alqasoumi, S. I., Awaad, A. S., & Cracker, L. (2011). Antioxidant activity of Covolvulus hystrix Vahl and its chemical constituents. Pak. J. Pharm. Sci, 24(2), 143-147.
Abstract:	Total alcohol and successive extracts (diethyl ether, chloroform, ethyl acetate and n-butanol) of Covolvulus hystrix Vahl were screened for their antioxidant activity using free radical 2-2- diphenyl-1-picrylhydrazyl (DPPH) and Trolox as reference substance. The tested extracts showed variable antioxidant activities. The highest antioxidant activity was achieved in total alcohol (48.32%) followed by ethyl acetate (37. 8 %) and nbutanol (32.96 %) extracts. From the ethyl acetate extract four compounds were isolated and identified as quercetin, quercetin 3-0-rutinoside and quercetin-7-O-rhamnoside in addition to ferulic acid using different spectroscopic analysis such as, 1 HNMR, 13CNMR, COSY, HMBC and HMQC
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/16431
ISSN:	1011-601X
Appears in Collections:	Issue 02

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