Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/16451
Title: REVIEW DOES VITAMIN E HAVE A ROLE IN TREATMENT AND PREVENTION OF ANEMIA’S?
Authors: TANVEER JILANI
MOHAMMAD PERWAIZ IQBAL
Keywords: Anemia
antioxidant
vitamin E
Issue Date: 23-Apr-2011
Publisher: Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi
Citation: Jilani, T., & Iqbal, M. P. (2011). Does vitamin E have a role in treatment and prevention of anemia?. Pakistan journal of pharmaceutical sciences, 24(2), 237.
Abstract: Vitamin E is a highly effective fat-soluble vitamin with a variety of cellular membrane stabilizing-antioxidant and non-antioxidant functions. Vitamin E has been suggested to prevent the oxidation of polyunsaturated fatty acids in red blood cell (RBC) membrane, thus inhibiting the premature erythrocytelysis. Animal studies have shown that treatment with vitamin E results in increased number of colony forming units of erythroid precursors, enhanced erythropoiesis and improved blood hemoglobin levels in these animals. Several clinical trials have indicated that vitamin E might be used therapeutically as a potential erythropoietic agent for decreasing the premature erythrocyte hemolysis by reducing the fragility of erythrocytes. By this way, it improves the post-supplemental blood hemoglobin and hematocrit levels in some of the anemic human subjects, including low birth weight premature infants, patients suffering from various types of inherited hemolytic anemia, chronic renal failure patients on hemodialysis and apparently healthy mildly anemic subjects.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/16451
ISSN: 1011-601X
Appears in Collections:Issue 02

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