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Please use this identifier to cite or link to this item: http://142.54.178.187:9060/xmlui/handle/123456789/16526
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dc.contributor.authorMUHAMMAD TAYYAB ANSARI-
dc.contributor.authorBASHIR AHMED LOOTHAR-
dc.contributor.authorKHAN, QASIM JAHANGIR-
dc.date.accessioned2023-01-20T09:31:22Z-
dc.date.available2023-01-20T09:31:22Z-
dc.date.issued1999-01-05-
dc.identifier.citationANSARI, M. T., LOOTHAR, B. A., & KHAN, Q. J. (1999). Pharmacokinetic study about interaction of Naproxen and Isoniazid. Pakistan Journal of Pharmaceutical Sciences, 12(1), 27-32.en_US
dc.identifier.issn1011-601X-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/16526-
dc.description.abstractEffect of Naproxen (500 mg) was studied on the pharmacokinetic characteristics of Isoniazed (300 mg) in ten healthy human volunteers in a complete cross-over design. A high performance liquid chromatography (HPLC) method was used to analyze serum drug concentrations. Naproxen caused a highly significant (P<0.001) increase in AUC, significant (P<0.05) increase in elimination half life (t1/2) and time for the maximum drug concentration (tmax) while significant (P<0.05) decrease in elimination rate constant (Ke). Insignificant decrease and increase was observed in absorption rate constant (Ka) and maximum drug concentration (Cmax) respectively.en_US
dc.language.isoenen_US
dc.publisherKarachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachien_US
dc.titlePHARMACOKINETIC STUDY ABOUT INTERACTION OF NAPROXEN AND ISONIAZIDen_US
dc.typeArticleen_US
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