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Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/16527
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dc.contributor.authorN.M. RANJHA-
dc.date.accessioned2023-01-20T09:31:38Z-
dc.date.available2023-01-20T09:31:38Z-
dc.date.issued1999-01-06-
dc.identifier.citationRanjha, N. M. (1999). Swelling behaviour of pH-sensitive crosslinked poly (vinyl acetate co-acrylic acid) hydrogels for site specific drug delivery. Pakistan journal of pharmaceutical sciences, 12(1), 33-41.en_US
dc.identifier.issn1011-601X-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/16527-
dc.description.abstractThe present work was undertaken to combine nonionic vinyl acetate (VAC) with anionic acrylic acid (AA) or methacrylic acid (MAA) monomers in the presence of ethylen glycol dimethacrylate (EGDMA) as crosslinking agent through radical polymerization. Poly (vinyl acetate-co-acrylic acid) VAC/AA 50:50 to 100:0 six samples and Poly(vinvl acetatecomethacrylic acid) VAC/MAA one sample were prepared. All the samples were used for swelling studies. High swelling occurred at above pH 5.5 through chain relaxation. It was observed that swelling to VAC/MAA was lower than VAC/AA copolymers. The lower swelling in VAC/MAA copolymer is due to the presence of hydrophobic methyl group and higher pKa value of this copolymer.en_US
dc.language.isoenen_US
dc.publisherKarachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachien_US
dc.titleSWELLING BEHAVIOUR OF pH-SENSITIVE CROSSLINKED POLY(VINYL ACETATE CO-ACRYLIC ACID) HYDROGELS FOR SITE SPECIFIC DRUG DELIVERYen_US
dc.typeArticleen_US
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