NEUROCHEMICAL AND BEHAVIOURAL EFFECTS OF LONG TERM INTAKE OF TEA

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Title:	NEUROCHEMICAL AND BEHAVIOURAL EFFECTS OF LONG TERM INTAKE OF TEA
Authors:	SAIDA HAIDER ANILA YASMEEN TAHIRA PARVEEN DARAKHSHAN J. HALEEM
Issue Date:	8-Jul-1998
Publisher:	Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi
Citation:	Haider, S. A. I. D. A., Yasmeen, A. N. I. L. A., Parveen, T. A. H. I. R. A., & Haleem, D. J. (1998). Neurochemical and behavioural effects of long term intake of tea. Pak J Pharm Sci, 11(2), 55-60.
Abstract:	Tea consumption in many cases is the main source of caffeine intake in humans. In the present study neurochemical and behavioural effects of long term tea intake are monitored in rats. Long term tea administration did not alter plasma tryptophan (TRP) but significantly attenuated brain TRP and 5-hydorxtryptamine (5-HT, serotonin) levels. Brain 5-hydroxyindole acetic acid (5-HIAA) was comparable in both tea-treated and control rats. An increase in home cage activity was observed after one week in rats taking tea as sole source of liquid, whereas no change on the activity was observed in an open field. Caffeinism has been associated with depression. The decreases of brain monoamine metabolism observed in present study are discussed as lowering of mood observed in tea or coffee consumers.
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/16536
ISSN:	1011-601X
Appears in Collections:	Issue 2

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