Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/16611
Title: Effect of cimetidine, ranitidine and tiotidine on plasma testosterone and luteinizing hormone levels in rats
Authors: R T Mahmud
M S Akhter
Issue Date: 6-Jan-1994
Publisher: Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi
Citation: Mahmud, R. T., & Akhter, M. S. (1995). Effect of cimetidine, ranitidine and tiotidine on plasma testosterone and luteinizing hormone levels in rats. Pakistan Journal of Pharmaceutical Sciences, 8(1), 45-50.
Abstract: This investigation was carried out to study the comparative effects of cimetidine, ranitidine and tiotidine on the plasma levels of testosterone and luetinizing hormone under local conditions. The three H(2)-blocking drugs were injected to the adult male albino rats twice daily at the recommended therapeutic dose levels for six weeks. The data obtained showed that only tiotidine caused a significant (<0.05) increase in the level of testosterone. However, all the three drugs caused a significant rise in the levels of luteinizing hormone with the most active ranitidine administration.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/16611
ISSN: 1011-601X
Appears in Collections:Issue No. 1

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