Effect of cobalt (ii), copper (ii), nickel (ii) and zinc(ii) metal ions on the biological activity of triazine derived ligand

Abstract

A new Schiff-base triazine-derived ligand and its cobalt (II), copper (II), nickel (II) and zinc (II) metal complexes have been synthesised and characterised on the basis of elemental analysis, molar conductance, infrared, HNMR and electronic spectral, and magnetic susceptibility data. In order to asssess the effect of metal ions on the antibacterial activity, the ligand and its complexes have been screened against bacterial species Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. In all cases the activity/potency has substantially increased on complexation against one or more bacterial species.