Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/16631
Title: Haemolytic assay for the detection of adenylate cyclase toxin of Bordetella pertussis
Authors: Y F Kazi
R Parton
B A Memon
Issue Date: 6-Jul-1994
Publisher: Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi
Citation: Kazi, Y. F., Parton, R. O. G. E. R., & Memon, B. A. (1994). Haemolytic assay for the detection of adenylate cyclase toxin of Bordetella pertussis. Pak J Pharm Sci, 7(2), 55-9.
Abstract: The aim of this study was to device a simple, sensitive and convenient assay for the detection of toxicity of the Adenylate cyclase toxin (ACT), a newly recognized toxin of Bordetella pertussis. Haemolytic activity of ACT was analysed as an assay and sheep RBCs were found to be suitable to detect the toxic effect down to the dose of 6.25 nmol cAMP/min/ml enzymic activity applied. The haemolytic activity was found to be dose-dependent.
URI: http://142.54.178.187:9060/xmlui/handle/123456789/16631
ISSN: 1011-601X
Appears in Collections:Issue No. 2

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