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http://142.54.178.187:9060/xmlui/handle/123456789/16653| Title: | Determination of astemizole by a spectrophotometric charge- transfer method |
| Authors: | O A Al-Deeb H A Al-Khamees M E Hagga M E Al-Awady |
| Issue Date: | 5-Jan-1994 |
| Publisher: | Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
| Citation: | AL-DEER, O. A., AL-KHAMEES, H. A., HAGGA, M. E., & AL-AWADY, M. E. (1994). Determination of astemizole by a Spectrophotometric charge-transfer method. Pakistan Journal of Pharmaceutical Sciences, 7(1), 43-50. |
| Abstract: | Iodine-astemizole charge-transfer complex has been utilized for the assay of astemizole. The complex formed in the proposed method shows strong absorption at 360 nm with a corresponding molar absorptivity. epsilon of 3.26 x 10 L mol1 cm-1 and obeyance of Beer's law over the concentration range 2-12 pg/mi. When the proposed method was applied to commercial tablets labeled to contain 10 mg of active ingredient per tablet, the mean percentage found was 99.72 +/- 1.36. Analysis of variance, (ANO VA), and added recovery experiments indicated adequate precision and accuracy for the method. |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/16653 |
| ISSN: | 1011-601X |
| Appears in Collections: | Issue No. 1 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| FULL TEXT.pdf | 130.91 kB | Adobe PDF |  View/Open |
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