EFFICACY OF COMBINATION OF AMOXICILLIN AND CLAVULANIC ACID IN THE TREATMENT OF PYODERMA IN BEETAL GOATS

Abstract

The present study was conducted in forty Beetal goats presented with severe-graded pyoderma on clinical grounds. These goats were treated with amoxicillin and clavulanic acid combi nation and compared with the treatment regimen already practiced in field i.e. co-trimazine. For this purpose, goats were randomly divided into two groups; A (control) and B (experimental), with 20 animals in each group. Group A was treated with co-trimazine, while group B was administered intramuscularly with amoxicillin and clavulanic acid combination at the rate of 15 mg/kg body weight (BW). At seventh day of treatment, goats of both groups were evaluated for comparative efficacy of two treatment protocols through observing the clinical manifestations of disease. Complete clinical cure of the lesions or a marked improvement was set as the main criterion for evaluation of efficacy of drugs. In group B, 18 (90%) goats showed clinical cure of therapy, while cure rate in group A was 11 (55%) which showed a significant difference (P < 0.05) in success rate of treatment protocol in group B over its counterpart (group A). The results of the study have shown that that severe cases of pyoderma in goats could be effectively treated with the combination of amoxicillin and clavulanic acid.