COMPARATIVE PROFILING OF PHYTOCHEMICAL CONTENTS AND RADICAL SCAVENGING POTENTIAL IN SOME SPECIES OF FAMILY MORACEAE

Abstract

The current study was carried out for comparative estimation of phytochemicals, anti-radical properties and half maximal inhibitory concentration (IC50) of seven species of family Moraceae using 2, 2-Diphenyl-1-Picrylhydrazyl assay. Methanolic (70%) extraction of crude leaves extracts was done via Double Maceration technique. Quantitative assay for determining the radical scavenging activity of DPPH as well as IC50 value of seven species of family Moraceae was observed. Results showed the presence of all major classes of phyto-compounds in seven species of family Moraceae, maximum percent inhibition radical scavenging activity was observed by Ficus infectoria (96±0.21) while minimum in Ficus macrophylla (scavenging >79.08%). Half maximal inhibitory concentration (IC50) of all the seven species of family Moraceae was done by Graph pad prism 5.04 software. Concentration dependent percent inhibition was observed in all the species of Family Moraceae. However all the selected species had significant antioxidant potential which indicated the pharmaceutical uses of all the species under study on commercial scale in near future.