In search of an alleviating drug in the management of mastalgia, danazol or evening primerose oil: our recent experience

Abstract

Objective: To study the recent outcomes of management of mastalgia treated by Danazol and Evening Primerose oil. Study design: Descriptive observational study Study sett ing: Department of Surgery, Hamdard University Hospital Duration: For a period of 12 months: from December 2016 to December 2017 Material and Methods: Th e candidates were selected on basis of double blinded, consecutive sampling. Females with complains of Mastalgia, coinciding with our inclusion criteria were administered danazol, evening primerose oil in divided doses for a period of 6 weeks and they were assessed for pain alleviation by the Cardiff Breast Pain score. Results: In our study the results showed Danazol to be signifi cantly eff ective in the management of Mastalgia as compared to the effi cacy of evening primrose oil. In Group-A, the average Cardiff breast pain score of those candidates receiving Danazol at 4 weeks was 2.19 and at 12 weeks was 1.23, which signifi es the effi cacy of the drug in relieving pain. Th e Mean Cardiff breast pain score of group-B at 4 weeks was 2.77 and at 12 weeks was 2.03 reinforcing its use not strongly benefi cial for patients in mastalgia. Conclusion: We concluded that although with mild, tolerable and reversible adverse eff ects Danazol has a promising role in management of cyclical in women.