Micro-organism culture and antibiotic sensitivity patt ern isolated from diabetic foot infections at tertiary care hospital, Mardan

Abstract

Objective: Diabetic foot infection is leading cause of lower extremity amputation and are preventable if appropriate treatment is given. Th is study assesses the micro-organism culture of patients with diabetic foot infections and their antibiotic susceptibility patt ern. Study design: Cross-sectional study. Sett ing and duration: Surgical Department of Mardan Medical Complex, Mardan from June 2017 to May 2018 Material and Methods: 44 patients with diabetic foot infections of any age group and of both gender were included. Tissue from the foot wounds of diabetic patient was taken and sent for culture and antibiotic sensitivity. All the data was recorded on a standardized proforma and analyzed on SPSS version 21. Results: In this study 44 patients were included. Th e mean age of patients was 58.3±7.63 years with male to female ratio of 1:1.2. All patients had type-2 diabetes with right foot involvement in 27 patients and left foot in 17 patients. Single microorganism culture was obtained from 32 patients, polymicrobial culture from 8 patients and no growth found in 4 patients. Escherichia coli was the commonest organism isolated (35%) followed by Methicillin Resistant Staphylococcus Aureus (MRSA) 20% and Proteus (10%). Escherichia coli and Proteus were found sensitive to Carbapenems, Amikacin and Tazobactum piperacillin while MRSA was sensitive to Vancomycin and Linzolid. Conclusion: Gram-negative aerobes were the commonest organisms cultured with predominance of Escherichia coli followed by gram-positive aerobe MRSA in diabetic foot infections. Th is study helps us to choose empirical antibiotics for patients with diabetic foot infections